1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Trimethoprim 3-oxide

Trimethoprim 3-oxide (Synonyms: Trimethoprim 3-N-oxide)

Cat. No.: HY-100645 Purity: >98.0%
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Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim.

For research use only. We do not sell to patients.

Trimethoprim 3-oxide Chemical Structure

Trimethoprim 3-oxide Chemical Structure

CAS No. : 27653-67-4

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Estimated Time of Arrival: December 31
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Description

Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim[1].

In Vitro

Trimethoprim 3-oxide is the primary metabolite of trimethoprim[1].
Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates in human liver microsomes (HLMs). The CYP1A inhibitor α-Naphthoflavone inhibits Trimethoprim 3-oxide formation, however, other competitive P450 inhibitors has no obvious inhibition on the formation[1].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

306.32

Formula

C₁₄H₁₈N₄O₄

CAS No.

27653-67-4

SMILES

NC1=NC=C(CC2=CC(OC)=C(OC)C(OC)=C2)C(N)=[N+]1[O-]

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Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Trimethoprim 3-oxide
Cat. No.:
HY-100645
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Trimethoprim 3-oxide

Cat. No.: HY-100645