A 438079 (Standard)
A 438079 (Standard) is the analytical standard of A 438079. This product is intended for research and analytical applications. A 438079 is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.
For research use only. We do not sell to patients.
- CAS No.: 899507-36-9
- Formula: C13H9Cl2N5
- Molecular Weight:306.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 899507-36-9
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Molecular Weight 306.15
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Formula C13H9Cl2N5
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SMILES
ClC1=C(Cl)C(C2=NN=NN2CC3=CC=CN=C3)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. McGaraughty S, et al. P2X7-related modulation of pathological nociception in rats. Neuroscience. 2007 Jun 8;146(4):1817-28. [Content Brief]
[2]. Mesuret G, et al. CNS Neurosci Ther. 2014 Jun;20(6):556-64. [Content Brief]
[3]. Marcellino D, et al. On the role of P2X(7) receptors in dopamine nerve cell degeneration in a rat model of Parkinson's disease: studies with the P2X(7) receptor antagonist A-438079. J Neural Transm (Vienna). 2010 Jun;117(6):681-7. [Content Brief]
[4]. Martins JP, et al. The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice. Br J Pharmacol. 2012 Jan;165(1):183-96. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A 438079 (Standard) Related Classifications
HY-15488R Related Classifications
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