2. GPCR/G Protein
  3. Adenosine Receptor
  4. A2AAR antagonist 2

3′-Methoxyfurano[4″,5″:3,4]chalcone (compound 2) is a selective A2AAR antagonist (IC50=33.5 nM) with high affinity. 3′-Methoxyfurano[4″,5″:3,4]chalcone is also a natural product obtained from the bark of Allium cepa L. 3′-Methoxyfurano[4″,5″:3,4]chalcone can promote T cell activation and can be used in cancer immunity research.

For research use only. We do not sell to patients.

A2AAR antagonist 2 Chemical Structure

A2AAR antagonist 2 Chemical Structure

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A2AAR antagonist 2 Related Antibodies

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Description

3′-Methoxyfurano[4″,5″:3,4]chalcone (compound 2) is a selective A2AAR antagonist (IC50=33.5 nM) with high affinity. 3′-Methoxyfurano[4″,5″:3,4]chalcone is also a natural product obtained from the bark of Allium cepa L. 3′-Methoxyfurano[4″,5″:3,4]chalcone can promote T cell activation and can be used in cancer immunity research[1].

IC50 & Target[1]

A2a adenosine receptor

33.5 nM (IC50)

Molecular Weight

278.30

Formula

C18H14O3
SMILES

O=C(/C=C/C1=CC(C=CO2)=C2C=C1)C3=CC=CC(OC)=C3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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A2AAR antagonist 2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A2AAR antagonist 2Adenosine ReceptorP1 receptorAllium cepa L.cancerinflammationT cellnatural productInhibitorinhibitorinhibit

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