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Cat. No.: HY-157254

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AA10

AA10 is a potent and irreversible transglutaminase 2 (TG2) inhibitor for cancer research.

For research use only. We do not sell to patients.

CAS No.: 2134106-02-6
Formula: C₃₂H₃₆N₄O₅
Molecular Weight:556.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

AA10 Chemical Structure

CAS No.: 2134106-02-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

AA10 is a potent and irreversible transglutaminase 2 (TG2) inhibitor for cancer research^[1].

Chemical Information

CAS No. 2134106-02-6
Molecular Weight 556.65
Formula C₃₂H₃₆N₄O₅
SMILES

O=C(OCC1=CC=CC=C1)N[C@H](C(N2CCN(C(C3=CC=C4C=CC=CC4=C3)=O)CC2)=O)CCCCNC(C=C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Akbar A, et al. Structure-Activity Relationships of Potent, Targeted Covalent Inhibitors That Abolish Both the Transamidation and GTP Binding Activities of Human Tissue Transglutaminase. J Med Chem. 2017 Sep 28;60(18):7910-7927. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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