ABD-3001
ABD-3001 is an inhibitor of ALDH1. ABD-3001 can be studied in research on refractory/relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome.
For research use only. We do not sell to patients.
- CAS No.: 350229-29-7
- Formula: C9H15NOS
- Molecular Weight:185.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | IC50 |
6 μM
Compound: 2a, DIMATE
|
Growth inhibition of human DU145 cells
Growth inhibition of human DU145 cells
|
[PMID: 17692435] |
| DU-145 | IC50 |
7.2 μM
Compound: 2a, DIMATE
|
Growth inhibition of human DU145 cells administered after 3 days
Growth inhibition of human DU145 cells administered after 3 days
|
[PMID: 17692435] |
| MRC5 | IC50 |
8 μM
Compound: 2a, DIMATE
|
Growth inhibition of human MRC5 cells
Growth inhibition of human MRC5 cells
|
[PMID: 17692435] |
| RH7777 | IC50 |
10 μM
Compound: 2a, DIMATE
|
Growth inhibition of RH7777 cells
Growth inhibition of RH7777 cells
|
[PMID: 17692435] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 350229-29-7
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Molecular Weight 185.29
-
Formula C9H15NOS
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SMILES
O=C(SC)C#CC(C)(C)N(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)