2. Apoptosis
  3. Caspase
  4. Ac-LEHD-AMC

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity.

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Ac-LEHD-AMC

Ac-LEHD-AMC 화학구조

CAS No. : 292633-16-0

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg   견적 받기  
50 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Ac-LEHD-AMC Related Antibodies

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Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

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  • 순도&문서

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제품 설명

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].

분자량

711.72

화학식

C33H41N7O11
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)CC2=CN=CN2)=O)=O)C=C1O3)=CC3=O
선적

Room temperature in continental US; may vary elsewhere.
보관

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

용액&용해도
In Vitro: 

DMSO : 250 mg/mL (351.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4050 mL 7.0252 mL 14.0505 mL
5 mM 0.2810 mL 1.4050 mL 2.8101 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 98.96%

SDS (251 KB)

COA (249 KB) HNMR (287 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4050 mL 7.0252 mL 14.0505 mL 35.1262 mL
5 mM 0.2810 mL 1.4050 mL 2.8101 mL 7.0252 mL
10 mM 0.1405 mL 0.7025 mL 1.4050 mL 3.5126 mL
15 mM 0.0937 mL 0.4683 mL 0.9367 mL 2.3417 mL
20 mM 0.0703 mL 0.3513 mL 0.7025 mL 1.7563 mL
25 mM 0.0562 mL 0.2810 mL 0.5620 mL 1.4050 mL
30 mM 0.0468 mL 0.2342 mL 0.4683 mL 1.1709 mL
40 mM 0.0351 mL 0.1756 mL 0.3513 mL 0.8782 mL
50 mM 0.0281 mL 0.1405 mL 0.2810 mL 0.7025 mL
60 mM 0.0234 mL 0.1171 mL 0.2342 mL 0.5854 mL
80 mM 0.0176 mL 0.0878 mL 0.1756 mL 0.4391 mL
100 mM 0.0141 mL 0.0703 mL 0.1405 mL 0.3513 mL
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Ac-LEHD-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-LEHD-AMC292633-16-0CaspaseInhibitorinhibitorinhibit

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상품명:
Ac-LEHD-AMC
Cat. No.:
HY-D1652
수량:
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