Acetylaleuritolic acid
Acetylaleuritolic acid is a triterpenoid isolated from Jatropha curcas that exhibits tumor suppressive properties against the P-388 lymphocytic leukemia test system.
For research use only. We do not sell to patients.
- CAS No.: 28937-85-1
- Formula: C32H50O4
- Molecular Weight:498.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BJ | EC50 |
26.0417 μM
Compound: 2
|
Cytotoxicity against human BJ cells after 72 hrs by celltiter-glo assay
Cytotoxicity against human BJ cells after 72 hrs by celltiter-glo assay
|
[PMID: 23747806] |
| BV-2 | IC50 |
>50 μM
Compound: 11
|
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production measured after 24 hrs by Griess assay
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production measured after 24 hrs by Griess assay
|
[PMID: 30350995] |
| HEK293 | EC50 |
26.0417 μM
Compound: 2
|
Cytotoxicity against HEK293 cells after 72 hrs by celltiter-glo assay
Cytotoxicity against HEK293 cells after 72 hrs by celltiter-glo assay
|
[PMID: 23747806] |
| HepG2 | EC50 |
26.0417 μM
Compound: 2
|
Cytotoxicity against human HepG2 cells after 72 hrs by celltiter-glo assay
Cytotoxicity against human HepG2 cells after 72 hrs by celltiter-glo assay
|
[PMID: 23747806] |
| Raji | EC50 |
26.0417 μM
Compound: 2
|
Cytotoxicity against human Raji cells after 72 hrs by celltiter-glo assay
Cytotoxicity against human Raji cells after 72 hrs by celltiter-glo assay
|
[PMID: 23747806] |
| U-251 | IC50 |
8.4 μM
Compound: 5
|
Cytotoxicity against human U251 cells after 48 hrs by sulforhodamine B assay
Cytotoxicity against human U251 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 20958014] |
Chemical Information
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CAS No. 28937-85-1
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Molecular Weight 498.74
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Formula C32H50O4
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SMILES
CC(O[C@H]1CC[C@@]2([C@@H]3[C@@](C)(CC[C@H]2C1(C)C)C4=CC[C@]5(CCC(C)(C[C@H]5[C@@]4(CC3)C)C)C(O)=O)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)