AChE/MAO-B-IN-3
AChE/MAO-B-IN-3 (Compound D30) is a dual AChE and MAO-B inhibitor with IC50s of 0.0257 μM and 0.0456 μM against human AChE and MAO-B, respectively. AChE/MAO-B-IN-3 can be used for the research of Alzheimer’s disease.
For research use only. We do not sell to patients.
- Formula: C24H28N2O4
- Molecular Weight:408.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Aβ42 0.0074 μM (IC50) |
hAChE 0.0257 μM (IC50) |
hMAO-B 0.0456 μM (IC50) |
AChE/MAO-B-IN-3 (Compound D30) shows antioxidant activity with an IC50 of 0.246 ± 0.011 μM in the DPPH free-radical scavenging activity test[1].
AChE/MAO-B-IN-3 inhibits beta amyloid 1–42 (Aβ42) with an IC50 of 0.1780 ± 0.0074 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 408.49
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Formula C24H28N2O4
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SMILES
O=C(NC1=CC=C(/C=C(CC2=C3C=C(OC)C(OC)=C2)\C3=O)C=C1)CN(C)CCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)