Afatinib impurity 5
Based on 1 Customer Validation
Afatinib impurity 5 is an impurity of Afatinib (HY-10261).
For research use only. We do not sell to patients.
- Purity : 99.85%
- CAS No.: 402855-03-2
- Formula: C18H16ClFN4O2
- Molecular Weight:374.80
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Description
Chemical Information
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CAS No. 402855-03-2
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Appearance Solid
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Molecular Weight 374.80
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Formula C18H16ClFN4O2
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SMILES
NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@H]4COCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (66.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (249 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6681 mL | 13.3404 mL | 26.6809 mL | 66.7022 mL |
| 5 mM | 0.5336 mL | 2.6681 mL | 5.3362 mL | 13.3404 mL | |
| 10 mM | 0.2668 mL | 1.3340 mL | 2.6681 mL | 6.6702 mL | |
| 15 mM | 0.1779 mL | 0.8894 mL | 1.7787 mL | 4.4468 mL | |
| 20 mM | 0.1334 mL | 0.6670 mL | 1.3340 mL | 3.3351 mL | |
| 25 mM | 0.1067 mL | 0.5336 mL | 1.0672 mL | 2.6681 mL | |
| 30 mM | 0.0889 mL | 0.4447 mL | 0.8894 mL | 2.2234 mL | |
| 40 mM | 0.0667 mL | 0.3335 mL | 0.6670 mL | 1.6676 mL | |
| 50 mM | 0.0534 mL | 0.2668 mL | 0.5336 mL | 1.3340 mL | |
| 60 mM | 0.0445 mL | 0.2223 mL | 0.4447 mL | 1.1117 mL |