AKT-IN-21
AKT-IN-21 (compound C36) is a potent AKT inhibitor with broad-spectrum cytotoxicity and anticancer activity. AKT-IN-21 also blocks the cell cycle and induces apoptosis of cancer cells by down-regulating the PI3K/AKT pathway.
For research use only. We do not sell to patients.
- Formula: C26H34N2O4
- Molecular Weight:438.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
AKT-IN-21 shows anti-proliferation inhibitory activity and cytotoxcity among serval cancer cells, with IC50s of 2.33 μM (LNCaP), 2.38 μM (K562), 1.98 μM (HepG2), 3.95 μM (LX-2), respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 438.56
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Formula C26H34N2O4
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SMILES
COC1=C(C(/C=C/C2=CN=CC=C2)=O)C(O)=C(C/C=C(C)/C)C(OCCN(CC)CC)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AKT-IN-21 Related Classifications
HY-161144 Related Classifications
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