1. Protein Tyrosine Kinase/RTK
  2. ALK
  3. ALK-IN-5

ALK-IN-5 

Cat. No.: HY-128569
Handling Instructions

ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM.

For research use only. We do not sell to patients.

ALK-IN-5 Chemical Structure

ALK-IN-5 Chemical Structure

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Description

ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM[1].

IC50 & Target

IC50: 2.9 nM (ALK)[1]

In Vitro

ALK-IN-5 potently inhibits ALK with cellular IC50 of 27 nM[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

464.49

Formula

C₂₄H₂₅FN₆O₃

SMILES

O=C(C1=CN(C2=NNC(C)=C2)C3=NC(O[[email protected]](C4=NC=C(F)C=C4)C)=CC=C31)N5C[[email protected]](C)OCC5

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
ALK-IN-5
Cat. No.:
HY-128569
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ALK-IN-5

Cat. No.: HY-128569