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Cat. No.: HY-14162

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AM103 free acid

AM103 (free acid) is a selective FLAP inhibitor that can block the first step of the LT pathway, which is 5-LO activation. AM103 (free acid) can inhibit the production of LTB₄ and cysteinyl leukotrienes (CysLT). AM103 (free acid) has anti-inflammatory activity in a mouse model of chronic lung inflammation and can extend the survival time of mice injected with platelet-activating factor. AM103 (free acid) can be used for research on respiratory diseases such as asthma.

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CAS No.: 936349-47-2
화학식: C₃₆H₃₉N₃O₄S
분자량:609.78

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

AM103 free acid Chemical Structure

CAS No.: 936349-47-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information

CAS No. 936349-47-2
분자량 609.78
화학식 C₃₆H₃₉N₃O₄S
SMILES

O=C(C(C)(CC1=C(C2=C(N1CC3=CC=C(C4=CC=C(OC)N=C4)C=C3)C=CC(OCC5=NC=CC=C5)=C2)SC(C)(C)C)C)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lorrain D S, et al. Pharmacological characterization of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2, 2-dimethyl-propionic acid (AM103), a novel selective 5-lipoxygenase-activating protein inhibitor that reduces acute and chronic inflammation[J]. Journal of Pharmacology and Experimental Therapeutics, 2009, 331(3): 1042-1050.

Calculators

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Mass Mass

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Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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AM103 free acid

FEN1-IN-4

Fiboflapon

Veliflapon

Fiboflapon sodium

AM103

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

AM103 free acid

FEN1-IN-4

Fiboflapon

Veliflapon

Fiboflapon sodium

AM103

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

AM103 free acid Related Classifications

HY-14162 Related Classifications