Anti-inflammatory agent 60
Anti-inflammatory agent 60(compound 21) inhibitsnitric oxide production, with anIC50value of 12.95 μM.Anti-inflammatory agent 60reducesiNOS,phosphorylated p65, andβ-cateninexpression in a concentration-dependent manner.
For research use only. We do not sell to patients.
- Formula: C22H30O2
- Molecular Weight:326.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
12.95 μM[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | CC50 |
34.29 μM
Compound: 21
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Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell survival by MTT assay
Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell survival by MTT assay
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[PMID: 37852423] |
| RAW264.7 | IC50 |
12.95 μM
Compound: 21
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Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of NO release
Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of NO release
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[PMID: 37852423] |
Chemical Information
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Molecular Weight 326.47
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Formula C22H30O2
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SMILES
CC(C)(C1=CC(C(C)(C)C)=CC(CCC2=CC(O)=CC(O)=C2)=C1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lei M, et al. Design, Synthesis, anti-inflammatory activity Evaluation, preliminary exploration of the Mechanism, molecule Docking, and structure-activity relationship analysis of batatasin III analogs [published online ahead of print, 2023 Oct 16]. Bioorg Med Chem Lett. 2023;96:129527. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-inflammatory agent 60 Related Classifications
HY-156398 Related Classifications
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