1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 150

Antibacterial agent 150 (compound 5g) is an antibacterial agent with potent antibacterial activity against both Gram-positive bacteria and Gram-negative bacteria (MIC values ranging from 1-32 μg/mL). Antibacterial agent 150 can increase survival rate of MRSA (Methicillin-resistant Staphylococcus aureus)-infected mice.

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Antibacterial agent 150

Antibacterial agent 150 Chemical Structure

CAS No. : 2766604-30-0

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Description

Antibacterial agent 150 (compound 5g) is an antibacterial agent with potent antibacterial activity against both Gram-positive bacteria and Gram-negative bacteria (MIC values ranging from 1-32 μg/mL). Antibacterial agent 150 can increase survival rate of MRSA (Methicillin-resistant Staphylococcus aureus)-infected mice[1].

Cellular Effect
Cell Line Type Value Description References
A549 CC50
> 200 μM
Compound: 5g
Cytotoxicity against human A549 cells incubated for 24 hrs by CCK8 assay
Cytotoxicity against human A549 cells incubated for 24 hrs by CCK8 assay
[PMID: 37531743]
HEK293 CC50
34.55 μM
Compound: 5g
Cytotoxicity against HEK293 cells incubated for 24 hrs by CCK8 assay
Cytotoxicity against HEK293 cells incubated for 24 hrs by CCK8 assay
[PMID: 37531743]
HepG2 CC50
> 200 μM
Compound: 5g
Cytotoxicity against human HepG2 cells incubated for 24 hrs by CCK8 assay
Cytotoxicity against human HepG2 cells incubated for 24 hrs by CCK8 assay
[PMID: 37531743]
Molecular Weight

551.71

Formula

C33H45NO6

CAS No.
SMILES

O=C1CC[C@@]2([C@H]([C@@H]([C@](C=C)(C[C@H]([C@@]3([C@@H](CC2)C)C)OC(COC(/C=C/C4=CC=C(C=C4)N(C)C)=O)=O)C)O)C)[C@@]13[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Antibacterial agent 150 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Antibacterial agent 150
Cat. No.:
HY-155682
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