2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 329

Antibacterial agent 329 (Compound 9c) is an antibacterial agent. Antibacterial agent 329 inhibits the activity of MraY. Antibacterial agent 329 exhibits antibacterial activity against Escherichia coli K12 and Bacillus subtilis W23 with a MIC of 16 μg/mL, but shows no activity against Pseudomonas fluorescens Pf-5. Antibacterial agent 329 exerts antibacterial activity against Acinetobacter baumannii 19606, Staphylococcus aureus MRSA USA300 JE2, Enterobacter cloacae 19434, Klebsiella pneumoniae 700603 and Enterococcus faecium 19434, with MIC values of 8, 8, 16-32, 16-32 and 16 μg/mL, respectively, while it shows no activity against Pseudomonas aeruginosa NCTC 13437.

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Antibacterial agent 329

Antibacterial agent 329 Chemical Structure

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Antibacterial agent 329 Related Antibodies

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Description

Antibacterial agent 329 (Compound 9c) is an antibacterial agent. Antibacterial agent 329 inhibits the activity of MraY. Antibacterial agent 329 exhibits antibacterial activity against Escherichia coli K12 and Bacillus subtilis W23 with a MIC of 16 μg/mL, but shows no activity against Pseudomonas fluorescens Pf-5. Antibacterial agent 329 exerts antibacterial activity against Acinetobacter baumannii 19606, Staphylococcus aureus MRSA USA300 JE2, Enterobacter cloacae 19434, Klebsiella pneumoniae 700603 and Enterococcus faecium 19434, with MIC values of 8, 8, 16-32, 16-32 and 16 μg/mL, respectively, while it shows no activity against Pseudomonas aeruginosa NCTC 13437[1].

In Vitro

Antibacterial agent 329 exhibits antimicrobial activity against Escherichia coli K12 and Bacillus subtilis W23 with an MIC of 16 μg/mL, and no activity against Pseudomonas fluorescens Pf-5[1].
Antibacterial agent 329 exhibits antimicrobial activity against Acinetobacter baumannii 19606, Staphylococcus aureus MRSA USA300 JE2, Enterobacter cloacae 19434, Klebsiella pneumoniae 700603, and Enterococcus faecium 19434 with MIC values of 8, 8, 16-32, 16-32, and 16 μg/mL respectively, and no activity against Pseudomonas aeruginosa NCTC 13437[1].
Antibacterial agent 329 (200 μM) inhibits particulate Escherichia coli MraY activity by 33%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 329 Related Antibodies
Molecular Weight

333.31

Formula

C17H14F3N3O
SMILES

NC1=NC=C(N1)C2=CC=CC=C2OCC3=CC=C(C(F)(F)F)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antibacterial agent 329 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 329Antibacterial agent329Antibacterial agent-329BacterialBacillus subtilis W23Escherichia coli translocase MraYpeptidoglycan biosynthesis pathwayEscherichia coli K12Staphylococcus aureus MRSA USA300acinetobacter baumannii infectionstaphylococcus aureus mrsa infectionAcinetobacter baumannii 19606HepG2 cellsPseudomonas fluorescens Pf-5Inhibitorinhibitorinhibit

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