Anticancer agent 254
Based on 1 Customer Validation
Anticancer agent 254 (compound 10) is a dichloroacetic acid-loaded compound with enhanced antitumor activity against leukemia cells in vitro and better stability in vivo, and can be considered for preclinical evaluation of cancer inhibition.
For research use only. We do not sell to patients.
- CAS No.: 1841421-67-7
- Formula: C12H18Cl6N4O3
- Molecular Weight:479.01
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
0.34 mM
Compound: 10
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Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
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[PMID: 26653539] |
| JVM-2 | IC50 |
0.41 mM
Compound: 10
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Cytotoxicity against human JVM2 cells after 48 hrs by MTT assay
Cytotoxicity against human JVM2 cells after 48 hrs by MTT assay
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[PMID: 26653539] |
| Maver1 | IC50 |
0.55 mM
Compound: 10
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Cytotoxicity against human Maver1 cells after 48 hrs by MTT assay
Cytotoxicity against human Maver1 cells after 48 hrs by MTT assay
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[PMID: 26653539] |
| PBMC | IC50 |
1.26 mM
Compound: 10
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Cytotoxicity against human PBMC cells after 48 hrs by MTT assay
Cytotoxicity against human PBMC cells after 48 hrs by MTT assay
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[PMID: 26653539] |
Chemical Information
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CAS No. 1841421-67-7
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Appearance Solid
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Molecular Weight 479.01
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Formula C12H18Cl6N4O3
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Color White to off-white
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SMILES
ClC(C(NCCN(CCNC(C(Cl)Cl)=O)CCNC(C(Cl)Cl)=O)=O)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 254 Related Classifications
HY-119324 Related Classifications
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