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Cat. No.: HY-146511

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Anticancer agent 41

Anticancer agent 41 is a potent anticancer agent, shows a potent antitumor activity against MDA-MB-231 cell with an IC50 of 3.99 μM[1].

For research use only. We do not sell to patients.

CAS No.: 1394077-28-1
Formula: C₂₅H₁₈Br₂N₂O₃
Molecular Weight:554.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Anticancer agent 41 Chemical Structure

CAS No.: 1394077-28-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Anticancer agent 41 is a potent anticancer agent, shows a potent antitumor activity against MDA-MB-231 cell with an IC50 of 3.99 μM[1].

IC₅₀ & Target

IC₅₀: 3.99 μM (anticancer in MDA-MB-231 cell)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	>25 μg/mL Compound: 3h	Antiproliferative activity against human MCF7 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human MCF7 cells after 48 hrs by CCK-8 assay	[PMID: 22658083]
MDA-MB-231	IC₅₀	>10 μg/mL Compound: 3h	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK-8 assay	[PMID: 22658083]

Chemical Information

CAS No. 1394077-28-1
Molecular Weight 554.23
Formula C₂₅H₁₈Br₂N₂O₃
SMILES

COC1=CC2=C(NC(C)=C2C3=C(C(C(C4=C(NC5=C4C=CC=C5)C)=C(C3=O)Br)=O)Br)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jia J, Yin H, Chen C, et al. Design, synthesis, and evaluation of a novel series of mono-indolylbenzoquinones derivatives for the potential treatment of breast cancer. Eur J Med Chem. 2022 Apr 16;237:114375. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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