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Cat. No.: HY-151092

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Anticancer agent 77

Anticancer agent 77 (Compound 6c) shows anticancer activity, and can be widely used in synthesis and medicinal chemistry research.

For research use only. We do not sell to patients.

CAS No.: 2787582-75-4
Formula: C₂₅H₃₀BrN₇
Molecular Weight:508.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Anticancer agent 77 Chemical Structure

CAS No.: 2787582-75-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Anticancer agent 77 (Compound 6c) shows anticancer activity, and can be widely used in synthesis and medicinal chemistry research^[1].

In Vitro

Anticancer agent 77 (0-1 μM) can inhibit the proliferation of breast cancer cells^[1].
Anticancer agent 77 (0-1 μM; 24 h) can induce the apoptosis of breast cancer cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:

Glioma cells
Concentration:

0, 0.3, and 1 μM
Incubation Time:
Result:

Decreased the number of EdU positive cells in breast cancer in a concentration-dependent manner.

Apoptosis Analysis^[1]

Cell Line:

Breast cancer cells
Concentration:

0, 0.3, and 1 μM
Incubation Time:

24 hour
Result:

Promoted the apoptosis of breast cancer cells compared with the control group.

Chemical Information

CAS No. 2787582-75-4
Molecular Weight 508.46
Formula C₂₅H₃₀BrN₇
SMILES

CC(NC1=NC2=C(C=CC=C2)C(C3=NN=NN3C4CCCCC4)N1C5=CC=C(Br)C=C5)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jun Xiong, et al. Synthesis of 4-Tetrazolyl-Substituted 3,4-Dihydroquinazoline Derivatives with Anticancer Activity via a One-Pot Sequential Ugi-Azide/Palladium-Catalyzed Azide-Isocyanide Cross-Coupling/Cyclization Reaction. J Org Chem. 2022 Aug 5;87(15):9488-9496. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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