2. Anti-infection
  3. Bacterial
  4. Antitubercular agent-54

Antitubercular agent-54 is an antitubercular agent with potent intramacrophage activity (EC50 = 0.68 μM). Antitubercular agent-54 shows a MIC of 0.31 μM against Mycobacterium tuberculosis (Mtb) H37Rv in cholesterol-containing medium. Antitubercular agent-54 can be used for the research of tuberculosis.

For research use only. We do not sell to patients.

Antitubercular agent-54

Antitubercular agent-54 Chemical Structure

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Antitubercular agent-54 Related Antibodies

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Description

Antitubercular agent-54 is an antitubercular agent with potent intramacrophage activity (EC50 = 0.68 μM). Antitubercular agent-54 shows a MIC of 0.31 μM against Mycobacterium tuberculosis (Mtb) H37Rv in cholesterol-containing medium. Antitubercular agent-54 can be used for the research of tuberculosis[1].

In Vitro

Antitubercular agent-54 (Compound P39) exhibits potent inhibitory activity against Mtb in various metabolic states, with an EC50 of 0.68 μM against intramacrophage Mtb and an MIC of 0.31 μM against Mtb H37Rv in cholesterol-containing medium[1].
Antitubercular agent-54 (>40 μM) shows no significant cytotoxicity against HEK293T and HepG2 cells, with good safety profiles[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antitubercular agent-54 Related Antibodies
Parmacokinetics
Species Dose Route Note Cmax Tmax MRT0-last AUC0-last
Mice 20 mg/kg p.o. 文献审核 8533 ng/mL 8.0 h 7.23 h 58754 ng·h/mL
Molecular Weight

301.34

Formula

C15H19N5O2
SMILES

O=C(N)CN1N=C(C2=CC=C(OCC(C3CC3)C)C=C2)N=N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antitubercular agent-54 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitubercular agent-54Antitubercular agent54Antitubercular agent 54BacterialHEK293THepG2Inhibitorinhibitorinhibit

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