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Cat. No.: HY-184757

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Antitumor agent-224

Antitumor agent-224 is an antitumor agent associated with LD₅₀ toxicity in rats. Antitumor agent-224 exerts alkylating activity via the formation of aziridine intermediates, thereby interacting with biological macromolecules. Antitumor agent-224 exhibits activity against cancer cells and leukemia cells. Antitumor agent-224 can be used in the research of cancers such as leukemia.

For research use only. We do not sell to patients.

CAS No.: 1141-37-3
Formula: C₁₁H₁₃Cl₂NO₂
Molecular Weight:262.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antitumor agent-224 Chemical Structure

CAS No.: 1141-37-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

In Vivo

Antitumor agent-224 (compound 5) exhibits activity against Walker 256 rat carcinoma with an observed log 1/CED₉₀ of 3.81, and has an observed log 1/CLD₉₀ of 3.58^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1141-37-3
Molecular Weight 262.13
Formula C₁₁H₁₃Cl₂NO₂
SMILES

O=C(C1=CC=C(N(CCCl)CCCl)C=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Panthananickal A, et al. Structure-activity relationships in antitumor aniline mustards. J Med Chem. 1978 Jan;21(1):16-26. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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