Antiviral agent 49
Antiviral agent 49 (compound 4q) is dual antiviral and antibacterial agent. Antiviral agent 49 shows anti-enterococcus activity and anti-staphylococcal activity.
For research use only. We do not sell to patients.
- Formula: C31H32ClFN5O5P
- Molecular Weight:640.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
31.03 μM
Compound: 4q
|
Cytotoxicity against human Huh-7 cells
Cytotoxicity against human Huh-7 cells
|
[PMID: 38377828] |
| RD | CC50 |
>100 μM
Compound: 4q
|
Cytotoxicity against human RD cells
Cytotoxicity against human RD cells
|
[PMID: 38377828] |
| Vero C1008 | CC50 |
28.09 μM
Compound: 4q
|
Cytotoxicity against African green monkey Vero E6 cells
Cytotoxicity against African green monkey Vero E6 cells
|
[PMID: 38377828] |
Chemical Information
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Molecular Weight 640.04
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Formula C31H32ClFN5O5P
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SMILES
CC(C1=CC(F)=CC=C1N2CC3=CN(CC4=CC=C(O)C(C(P(OCC)(OCC)=O)NC5=CC=CC=C5Cl)=C4)N=N3)=CC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)