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Cat. No.: HY-134368

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Ap3A

Ap3A is a vasoactive molecule that regulates intracellular Ca²⁺ levels. Ap3A can promote the growth of vascular smooth muscle cells.

For research use only. We do not sell to patients.

CAS No.: 5959-90-0
Formula: C₂₀H₂₇N₁₀O₁₆P₃
Molecular Weight:756.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Ap3A Chemical Structure

CAS No.: 5959-90-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Ap3A is a vasoactive molecule that regulates intracellular Ca²⁺ levels. Ap3A can promote the growth of vascular smooth muscle cells^[1].

All Calcium Channel Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	0.06 μM Compound: Ap3A	Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase	[PMID: 16539385]

Chemical Information

CAS No. 5959-90-0
Molecular Weight 756.41
Formula C₂₀H₂₇N₁₀O₁₆P₃
SMILES

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1COP(OP(OP(OC[C@H]4O[C@@H](N5C=NC6=C5N=CN=C6N)[C@H](O)[C@@H]4O)(O)=O)(O)=O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Ca²⁺ Staining Technique
Ca²⁺ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca²⁺ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Szczepańska-Konkel M, et al. Effects of diadenosine polyphosphates on glomerular volume. Br J Pharmacol. 2005 Apr;144(8):1109-17. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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