country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-181893

Copy Link Print Information

Apoptosis inducer 60

Apoptosis inducer 60 (Compound 4a) is an Apoptosis inducer. Apoptosis inducer 60 induces concentration-dependent apoptosis in cells. Apoptosis inducer 60 exhibits moderate cytotoxicity against breast cancer cell lines.

For research use only. We do not sell to patients.

Formula: C₆₄H₅₆O₁₂
Molecular Weight:1017.12

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Apoptosis inducer 60 Chemical Structure

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Apoptosis inducer 60 (24 h) inhibits the viability of breast cancer MCF-7 cells, with an IC₅₀ value of 8.27 μM^[1].
Apoptosis inducer 60 (8.27-16.54 μM; 24 h) induces concentration-dependent apoptosis in breast cancer MCF-7 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis^[1]

Cell Line:

human breast cancer MCF-7 cells
Concentration:

8.27 μM (1× IC₅₀); 16.54 μM (2× IC₅₀)
Incubation Time:

24 h
Result:

Increased total apoptosis (early + late) to 16.45% (2.95% early apoptosis, 11.9% late apoptosis, 0.4% necrosis) at 8.27 μM.
Increased total apoptosis to 20.35% (8.65% early apoptosis, 11.7% late apoptosis, 0.9% necrosis) at 16.54 μM.
Showed a concentration-dependent decrease in cell density via microscopic observation.

Chemical Information

Molecular Weight 1017.12
Formula C₆₄H₅₆O₁₂
SMILES

OC1=C([C@H](C2=CC=C(OCC=C)C=C2)C3=C(O)C=C(O)C([C@@H](C4=CC=C(OCC=C)C=C4)C5=CC6=C(O)C=C5O)=C3)C=C([C@@H](C(C=C7)=CC=C7OCC=C)C8=CC([C@@H]6C(C=C9)=CC=C9OCC=C)=C(O)C=C8O)C(O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Fitria A, et al. Allyl-functionalized calix[4]resorcinarenes against breast cancer cells: Synthesis, cytotoxicity, apoptosis induction, and computational insights. Bioorg Med Chem Lett. 2026 Jun;135:130540. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote