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Cat. No.: HY-12798CR

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AR-13503 (Standard)

Name: AR-13503 (Standard)
Brand: MedChemExpress
SKU: HY-12798CR
Price: 300.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: AR-13324 M1 metabolite (Standard))

AR-13503 (Standard) (AR-13324 M1 metabolite (Standard)) is the analytical standard of AR-13503 (HY-12798C). This product is intended for research and analytical applications. AR-13503 (AR-13324 M1 metabolite) is the hydrolytic metabolite of AR-13324 mesylate. AR-13324 is a ROCK kinase and PKC inhibitor with anti-angiogenic and retinal health-improving effects, showing potential for use in retinal disease research.

For research use only. We do not sell to patients.

Purity : 0%
CAS No.: 2309668-15-1
Formula: C₁₉H₁₉N₃O₂
Molecular Weight:321.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AR-13503 (Standard) Chemical Structure

CAS No.: 2309668-15-1

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 2309668-15-1
Molecular Weight 321.38
Formula C₁₉H₁₉N₃O₂
SMILES

OCC1=CC=C([C@@H](CN)C(NC2=CC(C=CN=C3)=C3C=C2)=O)C=C1
Synonyms

AR-13324 M1 metabolite (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Ding J, et al. ROCK/PKC inhibitor AR-13503 inhibits angiogenesis and protects the barrier function of retinal pigment epithelium[J]. Investigative Ophthalmology & Visual Science, 2018, 59(9): 205-205.

[2]. Carbajal K, et al. AR-13503 Enhances the efficacy of aflibercept in a mouse model of proliferative diabetic retinopathy[J]. Investigative Ophthalmology & Visual Science, 2018, 59(9): 200-200.

[3]. Halasz E, et al. AR-13503, a ROCK inhibitor, reduces rod axon retraction during retinal detachment[J]. Investigative Ophthalmology & Visual Science, 2018, 59(9): 4221-4221.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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