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Art. -Nr.: HY-175906

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AR ligand-45

AR ligand-45 is an androgen receptor (AR) ligand, which can be used for the synthesis of PROTACs, such as SJH1-62B (HY-162241).

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₂H₂₅ClN₆O₂
Molecular Weight:440.93

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

AR ligand-45 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

AR ligand-45 is an androgen receptor (AR) ligand, which can be used for the synthesis of PROTACs, such as SJH1-62B (HY-162241)^[1].

Chemical Information

Molecular Weight 440.93
Formel C₂₂H₂₅ClN₆O₂
SMILES

O=C(C1=NN=C(N2CCNCC2)C=C1)NC3CCC(OC4=CC=C(C#N)C(Cl)=C4)CC3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Hong SH, et al. Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation. ACS Chem Biol. 2024 Feb 16;19(2):442-450. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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