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Art. -Nr.: HY-19292

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AS-601811

AS-601811(compound 47) is a 5alpha-reductase 1 inhibitor with the IC₅₀ of 20 nM and can be used for study of alopecia and hirsutism.

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CAS. Nr.: 194979-95-8
Formel: C₁₅H₁₇NO
Molecular Weight:227.30

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

AS-601811 Chemical Structure

CAS. Nr.: 194979-95-8

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
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Calculators
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Biologische Aktivität

Beschreibung

AS-601811(compound 47) is a 5alpha-reductase 1 inhibitor with the IC₅₀ of 20 nM and can be used for study of alopecia and hirsutism^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	20 nM Compound: 39	Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells	[PMID: 11020287]

Chemical Information

CAS. Nr. 194979-95-8
Molecular Weight 227.30
Formel C₁₅H₁₇NO
SMILES

O=C1CCN2C3=CC=C(C)C=C3CCC2=C1C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Occhiato EG, et al. Synthesis, biological activity, and three-dimensional quantitative structure-activity relationship model for a series of benzo[c]quinolizin-3-ones, nonsteroidal inhibitors of human steroid 5alpha-reductase 1. J Med Chem. 2004;47(14):3546-3560. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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AS-601811

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Finasteride acetate

CGP-53153

5α-reductase-IN-1

8,11-Eicosadiynoic acid

LY191704

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Chemical Information

Reinheit & Dokumentation

Verweise

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Help & FAQs

Bioz

AS-601811

Dutasteride

Epristeride

Dutasteride (Standard)

Epristeride (Standard)

MK 386

Finasteride acetate

CGP-53153

5α-reductase-IN-1

8,11-Eicosadiynoic acid

LY191704

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

AS-601811 Related Classifications

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