Ascr#14
Ascr#14 (Asc-C8) is an ascaroside derivative that exhibits low activity in inducing the dauer (dormant larval) stage.
For research use only. We do not sell to patients.
- CAS No.: 1355681-47-8
- Formula: C14H26O6
- Molecular Weight:290.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Asc-C8 (220-6000 nM; 68-72 h) induces dauer formation in Caenorhabditis elegans larvae, with ~15% induction at 220 nM and ~60% induction at 6000 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1355681-47-8
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Molecular Weight 290.36
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Formula C14H26O6
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SMILES
O([C@@H](CCCCCC(O)=O)C)[C@H]1[C@H](O)C[C@@H](O)[C@H](C)O1
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Synonyms
Asc-C8
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hollister KA, et al. Ascaroside activity in Caenorhabditis elegans is highly dependent on chemical structure. Bioorg Med Chem. 2013;21(18):5754-5769. [Content Brief]
[2]. Bhar S, et al. Comparative Metabolomics Identifies the Roles of Acyl-CoA Oxidases in the Biosynthesis of Ascarosides and a Complex Family of Secreted N-Acylethanolamines. ACS Chem Biol. 2025;20(6):1298-1308. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)