AT-9010 triethylamine
Based on 1 publication(s) in Google Scholar
AT-9010 triethylamine，a triphosphate active metabolite of AT-527，is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 triethylamine can inhibit SARS-CoV-2 replication.
For research use only. We do not sell to patients.
- CAS No.: 2648089-95-4
- Formula: C35H77FN9O13P3
- Molecular Weight:943.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) AT-9010 triethylamine
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Biological Activity
NiRAN[1]
Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 μM AT-511 (698 μM and 236 μM，respectively)，with a half-life of at least 38 hours[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2648089-95-4
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Molecular Weight 943.96
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Formula C35H77FN9O13P3
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SMILES
O[C@H]1[C@](F)(C)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O[C@@H]1COP(O)(OP(OP(O)(O)=O)(O)=O)=O.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell
A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. [Abstract]2022 Nov 10;185(23):4347-4360.e17. PMID: 36335936
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AT-9010 triethylamine Related Classifications
HY-139165B Related Classifications
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