4-Nitropyrazole
Based on 1 Customer Validation
4-Nitropyrazole is a five-membered nitrogen-containing heterocyclic compound that can be used as a drug intermediate. 4-Nitropyrazole can be synthesized into antibiotics/antifungal/antiviral agents containing pyrazole rings. 4-Nitropyrazole is synthesized through C-H activation reactions to produce LRRK2 inhibitors, which are used in the research of Parkinson's disease.
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- Reinheit: 99.99%
- CAS. Nr.: 2075-46-9
- Formel: C3H3N3O2
- Molecular Weight:113.08
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 2075-46-9
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Appearance Solid
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Molecular Weight 113.08
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Formel C3H3N3O2
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Color White to off-white
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SMILES
O=[N+](C1=CNN=C1)[O-]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 200 mg/mL (1768.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Manfredini S,et al. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides. J Med Chem. 1992 Mar 6;35(5):917-24. [Content Brief]
[2]. Barron B, et al. A Concise Enantioselective Synthesis of Fluorinated Pyrazolo-Piperidine GSK3901383A Enabled by an Organocatalytic Aza-Michael Addition. Org Lett. 2024 Mar 1;26(8):1533-1538. [Content Brief]
[3]. Hrelia P, et al. Synthesis, metabolism and structure-mutagenicity relationships of novel 4-nitro-(imidazoles and pyrazoles) in Salmonella typhimurium. Mutat Res. 1998 Feb 2;397(2):293-301. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 8.8436 mL | 44.2180 mL | 88.4361 mL | 221.0902 mL |
| 5 mM | 1.7687 mL | 8.8436 mL | 17.6872 mL | 44.2180 mL | |
| 10 mM | 0.8844 mL | 4.4218 mL | 8.8436 mL | 22.1090 mL | |
| 15 mM | 0.5896 mL | 2.9479 mL | 5.8957 mL | 14.7393 mL | |
| 20 mM | 0.4422 mL | 2.2109 mL | 4.4218 mL | 11.0545 mL | |
| 25 mM | 0.3537 mL | 1.7687 mL | 3.5374 mL | 8.8436 mL | |
| 30 mM | 0.2948 mL | 1.4739 mL | 2.9479 mL | 7.3697 mL | |
| 40 mM | 0.2211 mL | 1.1055 mL | 2.2109 mL | 5.5273 mL | |
| 50 mM | 0.1769 mL | 0.8844 mL | 1.7687 mL | 4.4218 mL | |
| 60 mM | 0.1474 mL | 0.7370 mL | 1.4739 mL | 3.6848 mL | |
| 80 mM | 0.1105 mL | 0.5527 mL | 1.1055 mL | 2.7636 mL | |
| 100 mM | 0.0884 mL | 0.4422 mL | 0.8844 mL | 2.2109 mL |
4-Nitropyrazole Related Classifications
HY-W002458 Related Classifications
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