FBPase-IN-5
Based on 1 Customer Validation
MB-07729 is a potent fructose 1,6-bisphosphatase (FBPase) noncompetitive inhibitor with IC50 values of 31, 121, and 189 nM for human, monkey, and rat, respectively.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.31%
- CAS. Nr.: 882755-95-5
- Formel: C12H15N2O5PS
- Molecular Weight:330.30
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
IC50: 31 nM (human), 121nM (monkey), and 189 nM (rat) [1] .
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | EC50 |
140 nM
Compound: MB07729
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Inhibition of glucose production in human hepatocyte assessed as reduction in blood glucose level
Inhibition of glucose production in human hepatocyte assessed as reduction in blood glucose level
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[PMID: 29055870] |
Chemical Information
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CAS. Nr. 882755-95-5
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Appearance Solid
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Molecular Weight 330.30
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Formel C12H15N2O5PS
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Color White to off-white
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SMILES
CC(C)(C)C(C1=C(C2=CC=C(P(O)(O)=O)O2)N=C(N)S1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
FBPase-IN-5 Related Classifications
HY-16308 Related Classifications
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