Antimicrobial agent-41
Antimicrobial agent-41 (Compound 19) is a thiazolidinedione derivative. Antimicrobial agent-41 exhibits excellent antioxidant activity (IC50 = 27.66 μg/mL). Antimicrobial agent-41 also exhibits antidiabetic activity (IC50 = 40.01 μg/mL). Antimicrobial agent-41 has antimicrobial activity again both bacterial and fungi.
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- CAS. Nr.: 6325-95-7
- Formel: C12H11NO4S
- Molecular Weight:265.29
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
>100 μM
Compound: 18
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Antiproliferative activity against MCF7 cells after 72 hrs
Antiproliferative activity against MCF7 cells after 72 hrs
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[PMID: 17223347] |
| SK-BR-3 | IC50 |
>100 μM
Compound: 18
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Antiproliferative activity against SkBr3 cells after 72 hrs
Antiproliferative activity against SkBr3 cells after 72 hrs
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[PMID: 17223347] |
| SK-BR-3 | IC50 |
>100 μM
Compound: 18
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Induction of Hsp90-dependent Her2 protein degradation in Skbr3 cells after 24 hrs by ELISA
Induction of Hsp90-dependent Her2 protein degradation in Skbr3 cells after 24 hrs by ELISA
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[PMID: 17223347] |
Chemical Information
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CAS. Nr. 6325-95-7
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Appearance Solid
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Molecular Weight 265.29
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Formel C12H11NO4S
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Color White to off-white
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SMILES
O=C(NC/1=O)SC1=C\C2=CC=C(OC)C(OC)=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Protokoll
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Antimicrobial agent-41 Related Classifications
HY-131051 Related Classifications
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