BB-78485
BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials.
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- CAS. Nr.: 207732-11-4
- Formel: C23H20N2O4S
- Molecular Weight:420.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
IC50: 160 nM(LpxC)[1]
BB-78485 can inhibit LpxC with an IC50 value of 160 nM[1].
BB-78485 has effect against D21 and D22 (lpxC101) with MICs values of 2 μg/mL and 0.016 μg/mL, respectively[1].
BB-78485 shows predominantly gram-negative activities against members of the Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae, and Burkholderia cepacia with MICs values range from 1μg/mL to 32 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 207732-11-4
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Molecular Weight 420.48
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Formel C23H20N2O4S
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SMILES
O=C([C@@H](CC1=CC=C2C=CC=CC2=C1)NS(=O)(C3=CC=C4C=CC=CC4=C3)=O)NO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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