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Art. -Nr.: HY-N3630

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Coronarin D

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Coronarin D is a cytotoxic labdan-type diterpenes compound isolated from the rhizomes of H. coronarium.

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Reinheit: 97.0%
CAS. Nr.: 119188-37-3
Formel: C₂₀H₃₀O₃
Molecular Weight:318.45

Speicherung:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Coronarin D Chemical Structure

CAS. Nr.: 119188-37-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Coronarin D is a cytotoxic labdan-type diterpenes compound isolated from the rhizomes of H. coronarium^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	GI₅₀	8 μM Compound: 3	Growth inhibition of human A549 cells by Sulforhodamine B assay Growth inhibition of human A549 cells by Sulforhodamine B assay	[PMID: 21106458]
BMDC	IC₅₀	41.72 μM Compound: 4	Antiinflammatory activity in C57BL/6 mouse BMDC assessed as inhibition of LPS-stimulated TNF-alpha production preincubated for 1 hr before LPS-stimulation measured after 16 hrs by ELISA Antiinflammatory activity in C57BL/6 mouse BMDC assessed as inhibition of LPS-stimulated TNF-alpha production preincubated for 1 hr before LPS-stimulation measured after 16 hrs by ELISA	[PMID: 22071304]
HeLa	GI₅₀	47 μM Compound: 3	Growth inhibition of human HeLa cells by Sulforhodamine B assay Growth inhibition of human HeLa cells by Sulforhodamine B assay	[PMID: 21106458]
MCF7	GI₅₀	17.4 μM Compound: 3	Growth inhibition of human MCF7 cells by Sulforhodamine B assay Growth inhibition of human MCF7 cells by Sulforhodamine B assay	[PMID: 21106458]
SK-N-SH	GI₅₀	20.1 μM Compound: 3	Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay Growth inhibition of human SK-N-SH cells by Sulforhodamine B assay	[PMID: 21106458]

Chemical Information

CAS. Nr. 119188-37-3
Appearance Solid
Molecular Weight 318.45
Formel C₂₀H₃₀O₃
Color White to off-white
SMILES

CC1(C2C/C=C3C(OC(O)C\3)=O)C(CCC2=C)C(C)(CCC1)C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Itokawa H, et al. Cytotoxic diterpenes from the rhizomes of Hedychium coronarium. Planta Med. 1988;54(4):311-315. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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