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Art. -Nr.: HY-142025

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Daumone

Daumone is a natural product secreted by Caenorhabditis elegans. Daumone can be used for aging and obesity research and the development of anti-nematode drugs.

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CAS. Nr.: 690991-47-0
Formel: C₁₃H₂₄O₆
Molecular Weight:276.33

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Daumone Chemical Structure

CAS. Nr.: 690991-47-0

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Daumone is a natural product secreted by Caenorhabditis elegans. Daumone can be used for aging and obesity research and the development of anti-nematode drugs^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.02 μM Compound: Daumone	Growth inhibition of human A549 cells Growth inhibition of human A549 cells	[PMID: 28814374]
A549	IC₅₀	0.03 μg/mL Compound: 1	Anticancer activity against human A549 cells after 72 hrs by sulforhodamine B assay Anticancer activity against human A549 cells after 72 hrs by sulforhodamine B assay	[PMID: 19342127]
HCT-15	IC₅₀	0.05 μg/mL Compound: 1	Anticancer activity against human HCT15 cells after 72 hrs by sulforhodamine B assay Anticancer activity against human HCT15 cells after 72 hrs by sulforhodamine B assay	[PMID: 19342127]
SK-MEL-2	IC₅₀	0.07 μg/mL Compound: 1	Anticancer activity against human SK-MEL-2 cells after 72 hrs by sulforhodamine B assay Anticancer activity against human SK-MEL-2 cells after 72 hrs by sulforhodamine B assay	[PMID: 19342127]
SK-OV-3	IC₅₀	0.02 μg/mL Compound: 1	Anticancer activity against human SKOV3 cells after 72 hrs by sulforhodamine B assay Anticancer activity against human SKOV3 cells after 72 hrs by sulforhodamine B assay	[PMID: 19342127]
XF498	IC₅₀	0.09 μg/mL Compound: 1	Anticancer activity against human XF498 cells after 72 hrs by sulforhodamine B assay Anticancer activity against human XF498 cells after 72 hrs by sulforhodamine B assay	[PMID: 19342127]

Chemical Information

CAS. Nr. 690991-47-0
Molecular Weight 276.33
Formel C₁₃H₂₄O₆
SMILES

OC(CCCC[C@@H](C)O[C@H]1[C@@H](C[C@H]([C@@H](O1)C)O)O)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Animals
- Endogenous metabolite
Caenorhabditis elegans
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Jeong PY, et al. Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone. Nature. 2005 Feb 3;433(7025):541-5. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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