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Art. -Nr.: HY-N15015

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Dephostatin

Dephostatin is a competitive protein tyrosine phosphatase (PTP) inhibitor that can be isolated from Streptomyces spp., with activity in the micromolar range.

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CAS. Nr.: 151606-30-3
Formel: C₇H₈N₂O₃
Molecular Weight:168.15

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Dephostatin Chemical Structure

CAS. Nr.: 151606-30-3

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Dephostatin is a competitive protein tyrosine phosphatase (PTP) inhibitor that can be isolated from Streptomyces spp., with activity in the micromolar range^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Jurkat	IC₅₀	7.7 μM Compound: Dephostatin	Inhibition of human Jurkat cell membrane-derived protein tyrosine phosphatase using o-phospho-L-tyrosine as substrate incubated for 15 mins by by malachite green staining based assay Inhibition of human Jurkat cell membrane-derived protein tyrosine phosphatase using o-phospho-L-tyrosine as substrate incubated for 15 mins by by malachite green staining based assay	[PMID: 27687971]

Chemical Information

CAS. Nr. 151606-30-3
Molecular Weight 168.15
Formel C₇H₈N₂O₃
SMILES

O=NN(C)C1=CC(O)=CC=C1O
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ferreira CV, et al. Natural compounds as a source of protein tyrosine phosphatase inhibitors: application to the rational design of small-molecule derivatives. Biochimie. 2006 Dec;88(12):1859-73. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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