eIF4E-IN-6
eIF4E-IN-6(compound 4b) is a GMP analogs synthesized to targeteIF4Eand restrain its binding to cap mRNA.eIF4E-IN-6shows cell cytotoxicity against Caco-2, HepG-2,and MCF-7 cells, withIC50values of 31, 27, and 21 μM, respectively.
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- Formel: C33H32BrN9NaO12P
- Molecular Weight:880.53
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
31, 27, and 21 μM(Caco-2, HepG-2,and MCF-7)[1]
Chemical Information
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Molecular Weight 880.53
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Formel C33H32BrN9NaO12P
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SMILES
O=C1NC(NC(C2=CC=CC=C2)=O)=NC3=C1[N+](CC4=CC=CC=C4)=CN3C5OC(COP(NNC6=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C6)(O[Na])=O)C7C5OC(C)(C)O7.[Br-]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)