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Art. -Nr.: HY-105128

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Epostane

(Synonyms: WIN 32729)

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Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC₅₀ of 1.45 nM. Epostane blocks ovulation and pregnancy in rats.

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Reinheit: 99.0%
CAS. Nr.: 80471-63-2
Formel: C₂₂H₃₁NO₃
Molecular Weight:357.49

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Epostane Chemical Structure

CAS. Nr.: 80471-63-2

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Biologische Aktivität
- Beschreibung
- In Vivo
Chemical Information
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Bioz

Biologische Aktivität

Beschreibung

Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC₅₀ of 1.45 nM. Epostane blocks ovulation and pregnancy in rats^[1].

Alle 3β-HSD Isoform-spezifische Produkte anzeigen :

3β-HSD I

In Vivo

Epostane (0-200 mg/kg, p.o., single dose) inhibits ovulation in mature rats and gonadotropin-stimulated ovulation in immature rats, terminates pregnancy through lowering plasma progesterone levels^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Sprague Dawley rats model^[1]
Dosage:

0-200 mg/kg
Administration:

p.o., single dose
Result:

Terminated ovulation and pregnancy in rats, which was reversed by injections of progesterone.

Chemical Information

CAS. Nr. 80471-63-2
Appearance Solid
Molecular Weight 357.49
Formel C₂₂H₃₁NO₃
Color White to off-white
SMILES

C[C@@]12[C@@]3(CC[C@]4([H])[C@]2([H])CC[C@]5([C@@]4([H])CC[C@@]5(O)C)C)[C@](O3)(C(O)=C(C1)C#N)C
Synonyms

WIN 32729
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Snyder BW, et al., Inhibition of ovulation in rats with epostane, an inhibitor of 3 beta-hydroxysteroid dehydrogenase. Proc Soc Exp Biol Med. 1984 Jul;176(3):238-42. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Epostane

Alle 3β-HSD Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Epostane Related Classifications

HY-105128 Related Classifications