Etaconazol
Etaconazol (Etaconazole) is an azole fungicide. Etaconazol possesses endocrine-disrupting potential and inhibits placental steroidogenesis by suppressing 3β-hydroxysteroid dehydrogenase (3β-HSD1). Etaconazol binds to the NAD+/steroid-binding site of the target enzyme and acts on both the free enzyme and enzyme-substrate complex to inhibit their activity.
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- CAS. Nr.: 60207-93-4
- Formel: C14H15Cl2N3O2
- Molecular Weight:328.19
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Etaconazole (0-100 μM; 30 min) potently inhibits the activity of human placental microsomal 3β-HSD1, with an IC50 of 78 μM and a Ki of 88.9 μM[1].
Etaconazole (0-100 μM; 30 min) inhibits 3β-HSD4 activity in rat placental microsomes, with an IC50 of 102.6 μM and a Ki of 109.6 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 60207-93-4
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Molecular Weight 328.19
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Formel C14H15Cl2N3O2
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SMILES
ClC1=CC=C(C(Cl)=C1)C2(OCC(O2)CC)CN3N=CN=C3
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Synonyms
Etaconazole
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Etaconazol Related Classifications
HY-W714186 Related Classifications
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