FWM-1
Based on 1 Customer Validation
FWM-1 is a potent SARS-COV-2 NSP13 helicase enzyme inhibitor with binding free energy equals -328.6 kcal/mol. FWM-1 effectively disrupts the binding of ATP to the SARS-COV2 helicase enzyme.
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- Reinheit : 95.0%
- CAS. Nr.: 219542-52-6
- Formel: C15H11ClN4O4S2
- Molecular Weight:410.86
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
NSP13[1].
Chemical Information
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CAS. Nr. 219542-52-6
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Appearance Solid
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Molecular Weight 410.86
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Formel C15H11ClN4O4S2
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Color White to off-white
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SMILES
O=C1NC(NC(O)=C1C(C2=C(NC(NC2=O)=S)O)C3=CC=C(C=C3)Cl)=S
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 50 mg/mL (121.70 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4339 mL | 12.1696 mL | 24.3392 mL | 60.8480 mL |
| 5 mM | 0.4868 mL | 2.4339 mL | 4.8678 mL | 12.1696 mL | |
| 10 mM | 0.2434 mL | 1.2170 mL | 2.4339 mL | 6.0848 mL | |
| 15 mM | 0.1623 mL | 0.8113 mL | 1.6226 mL | 4.0565 mL | |
| 20 mM | 0.1217 mL | 0.6085 mL | 1.2170 mL | 3.0424 mL | |
| 25 mM | 0.0974 mL | 0.4868 mL | 0.9736 mL | 2.4339 mL | |
| 30 mM | 0.0811 mL | 0.4057 mL | 0.8113 mL | 2.0283 mL | |
| 40 mM | 0.0608 mL | 0.3042 mL | 0.6085 mL | 1.5212 mL | |
| 50 mM | 0.0487 mL | 0.2434 mL | 0.4868 mL | 1.2170 mL | |
| 60 mM | 0.0406 mL | 0.2028 mL | 0.4057 mL | 1.0141 mL | |
| 80 mM | 0.0304 mL | 0.1521 mL | 0.3042 mL | 0.7606 mL | |
| 100 mM | 0.0243 mL | 0.1217 mL | 0.2434 mL | 0.6085 mL |
FWM-1 Related Classifications
HY-144800 Related Classifications
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