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Art. -Nr.: HY-W440556

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GL-522

Name: GL-522
Brand: MedChemExpress
SKU: HY-W440556
Availability: PreOrder

(Synonyms: 4-Sulfocalix[8]arene)

GL-522 (4-Sulfocalix[8]arene) is a Aβ42 inhibitor. GL-522 bind to Aβ42 through nonspecific and multipoint hydrophobic interactions with a K_d of 276  μM. GL-522 effectively inhibits Aβ42 fibrillation and reduces amyloid cytotoxicity. GL-522 can be used for Alzheimer's disease research.

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CAS. Nr.: 137407-62-6
Formel: C₅₆H₄₈O₃₂S₈
Molecular Weight:1489.48

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

GL-522 Chemical Structure

CAS. Nr.: 137407-62-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

Chemical Information

CAS. Nr. 137407-62-6
Molecular Weight 1489.48
Formel C₅₆H₄₈O₃₂S₈
SMILES

O=S(O)(C1=CC(CC2=CC(S(=O)(O)=O)=CC(CC3=CC(S(=O)(O)=O)=CC(CC4=CC(S(=O)(O)=O)=CC(CC5=C(O)C(CC6=C(O)C(CC7=C(O)C(CC8=C(O)C(C9)=CC(S(=O)(O)=O)=C8)=CC(S(=O)(O)=O)=C7)=CC(S(=O)(O)=O)=C6)=CC(S(=O)(O)=O)=C5)=C4O)=C3O)=C2O)=C(O)C9=C1)=O
Synonyms

4-Sulfocalix[8]arene
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wang Z, et al. para-Sulfonatocalix[n]arenes Inhibit Amyloid β-Peptide Fibrillation and Reduce Amyloid Cytotoxicity. Chem Asian J. 2017 Feb 1;12(3):341-346. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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