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Art. -Nr.: HY-N19212

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Glenthmycin A

Glenthmycin A is a macrocyclic type II spiroketal polyketide antibacterial agent. Glenthmycin A inhibits the growth of Gram-positive pathogens. Glenthmycin A is applicable to the research of bacterial infections.

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CAS. Nr.: 3040055-59-9
Formel: C₄₉H₆₃NO₁₃
Molecular Weight:874.04

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Glenthmycin A Chemical Structure

CAS. Nr.: 3040055-59-9

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Glenthmycin A (Compound 1) (0.01-30 μM; 16-24 h) inhibits the growth of S. aureus ATCC 25923 (IC₅₀ 6.4 μM), E. faecalis (IC₅₀ 5.7 μM), MRSA ATCC 43300 (IC₅₀ 4.4 μM), MRSA ATCC 33591 (IC₅₀ 1.9 μM), and VRE (IC₅₀ 5.2 μM)^[1].
Glenthmycin A (30 μM; 48 h) does not exhibit significant cytotoxicity against human colorectal carcinoma (SW620) or human lung carcinoma (NCI-H460) cells, with IC₅₀ > 30 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3040055-59-9
Molecular Weight 874.04
Formel C₄₉H₆₃NO₁₃
SMILES

OC=1[C@@]23[C@@](C=C(C(O)=O)[C@H](C)C2)(/C=C(\C)/CC/C=C(\C)/[C@]4([C@@](C)(C(=O)C1C(=O)O3)[C@]5([C@@]([C@@H](O[C@H]6[C@H](O)[C@](C)(O)[C@H](NC(=O)C7=C(C)C=C(OC)C=C7O)[C@@H](C)O6)CC[C@@H]5C)(C=C4C)[H])[H])[H])[H]
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces sp.
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Wu T, et al. Glenthmycins A-M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived Streptomyces sp. CMB-PB041. J Nat Prod. 2022 Jun 24;85(6):1641-1657. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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