HJP 272
HJP 272 is a selective endothelin peptide A (ETA) receptor antagonist with an IC50 of 37.01 nM. . HJP 272 can be used for the researches of pulmonary arterial hypertension, fibrosis, renal failure and cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1072467-37-8
- Formel: C28H23NO8
- Molecular Weight:501.48
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
|
ETA 37.01 nM (IC50) |
ETB 15602.3 nM (IC50) |
HJP 272 (Compound 41) acts as an ETA-selective receptor antagonist in HEK293T cells, with an ETA IC50 of 37.01 nM and 421-fold selectivity over the ETB receptor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 1072467-37-8
-
Molecular Weight 501.48
-
Formel C28H23NO8
-
SMILES
O=C(C1=CC=CC(CC2=C(C(O)=O)N(CC3=CC4=C(C=C3CC)OCO4)C5=CC=C(O)C=C5C2=O)=C1)O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)