Juncusol
Juncusol, a phenanthrenoid found in Juncus setchuenensis, possesses anxiolytic effect. Juncusol is associated with metabolic changes in cortical serotonin/dopamine levels in Mice.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 62023-90-9
- Formel: C18H18O2
- Molecular Weight:266.33
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
12.5 μg/mL
Compound: 1a
|
In vitro cytotoxic activity against B-16 mouse melanoma (B-16)
In vitro cytotoxic activity against B-16 mouse melanoma (B-16)
|
[PMID: 4045930] |
| HEK293 | IC50 |
6.5 μM
Compound: 8
|
Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay
Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay
|
[PMID: 30892891] |
| L1210 | IC50 |
13.8 μg/mL
Compound: 1a
|
In vitro cytotoxic activity against L-1210 mouse lymphocytic leukemia cell culture (ATCC CCL-219)
In vitro cytotoxic activity against L-1210 mouse lymphocytic leukemia cell culture (ATCC CCL-219)
|
[PMID: 4045930] |
| RAW264.7 | IC50 |
3.1 μM
Compound: Juncusol
|
Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 48 hrs by Griess reagent assay
Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 48 hrs by Griess reagent assay
|
[PMID: 29280630] |
Chemical Information
-
CAS. Nr. 62023-90-9
-
Molecular Weight 266.33
-
Formel C18H18O2
-
SMILES
OC(C(C)=C1CC2)=CC=C1C3=C2C=C(O)C(C)=C3C=C
-
Structure Classification
-
Initial Source
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
-
Data Sheet (266 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Juncusol Related Classifications
HY-N5126 Related Classifications
Powered by Bioz