Leyk
Based on 1 Customer Validation
Leyk is an orally active Cysteine derivative. Leyk stimulates bone marrow hematopoiesis. Leyk exerts a significant protective effect against cyclophosphamide-induced leukopenia. Leyk can be used in studies related to thrombocytopenia and leukopenia.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.99%
- CAS. Nr.: 1950-36-3
- Formel: C14H17NO4S
- Molecular Weight:295.35
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:ICR mice (male, 18-22 g, cyclophosphamide-induced)[3]
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Dosage:20 mg/kg
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Administration:p.o.; daily; 1 week
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Result:Restored the percentage of eosinophils to normal levels.
Increased the percentage of basophils.
Increased peripheral white blood cell counts.
Increased peripheral platelet counts.
Increased bone marrow nuclear cell counts.
Enhanced bone marrow nuclear cell viability.
Promoted bone marrow mononuclear cell colony formation.
Reversed cyclophosphamide-induced elevated serum G-CSF and IL-6 levels to near-normal values.
Exhibited a network analysis Z-score of 10.823, indicating significant anti-leucopenia activity.
Chemical Information
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CAS. Nr. 1950-36-3
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Appearance Solid
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Molecular Weight 295.35
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Formel C14H17NO4S
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Color White to off-white
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SMILES
O=C(C1NC(C(C2=CC=CC=C2)C(OCC)=O)SC1)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (338.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (277 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Su M, et al. The therapeutic effect of leucogen in treating alcoholic liver cirrhosis with thrombocytopenia or leukopenia. Ann Saudi Med. 2025;45(1):9-17. [Content Brief]
[2]. Huang XE, et al. Leucogen tablets at 60 mg three times per day are safe and effective to control febrile neutropenia. Asian Pac J Cancer Prev. 2014;15(19):8495-8497. [Content Brief]
[3]. Tian S, et al. Systems Biology Analysis of the Effect and Mechanism of Qi-Jing-Sheng-Bai Granule on Leucopenia in Mice. Front Pharmacol. 2019 Apr 25;10:408. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3858 mL | 16.9291 mL | 33.8581 mL | 84.6453 mL |
| 5 mM | 0.6772 mL | 3.3858 mL | 6.7716 mL | 16.9291 mL | |
| 10 mM | 0.3386 mL | 1.6929 mL | 3.3858 mL | 8.4645 mL | |
| 15 mM | 0.2257 mL | 1.1286 mL | 2.2572 mL | 5.6430 mL | |
| 20 mM | 0.1693 mL | 0.8465 mL | 1.6929 mL | 4.2323 mL | |
| 25 mM | 0.1354 mL | 0.6772 mL | 1.3543 mL | 3.3858 mL | |
| 30 mM | 0.1129 mL | 0.5643 mL | 1.1286 mL | 2.8215 mL | |
| 40 mM | 0.0846 mL | 0.4232 mL | 0.8465 mL | 2.1161 mL | |
| 50 mM | 0.0677 mL | 0.3386 mL | 0.6772 mL | 1.6929 mL | |
| 60 mM | 0.0564 mL | 0.2822 mL | 0.5643 mL | 1.4108 mL | |
| 80 mM | 0.0423 mL | 0.2116 mL | 0.4232 mL | 1.0581 mL | |
| 100 mM | 0.0339 mL | 0.1693 mL | 0.3386 mL | 0.8465 mL |
Leyk Related Classifications
HY-118028 Related Classifications
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