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MEDI4212

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MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. MEDI4212 potently inhibits human IgE-mediated functional responses through its receptor FcεRI, such as calcium signaling, β-hexosaminidase release and phagocytosis. MEDI4212 prevents the binding of IgE to CD23 with an IC50 of 8 nM. MEDI4212 can be used severe asthma research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 98.06%
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for MEDI4212
  • MEDI4212 Chemical Structure
    MEDI4212 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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MEDI4212 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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  • 1/16

    Immobilized Human lgE Fc Protein, His Tag can bind MEDI4212. The EC50 for this effect is 46.7 ng/mL.

  • MEDI4212 Chemical Structure
    1/16
  • MEDI4212
  • Immobilized Human lgE Fc Protein, His Tag can bind MEDI4212. The EC50 for this effect is 46.7 ng/mL.