Art. -Nr.: HY-N7916

(-)-Menthone

(Synonyms: L-Menthone)

Kundenbewertung

Based on 1 Customer Validation

(-)-Menthone is a monoterpene component of the essential oil of maturing peppermint. (+)-Neomenthyl-β-d-glucoside is a metabolite of (-)-Menthone.Mortality of two biological forms of Anopheles stephensi(larvae) exposed to about 45 ppm (-)-Menthone is 27.67% and 94.92%.

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Reinheit: 98.0%

CAS. Nr.: 14073-97-3

Formel: C₁₀H₁₈O

Molecular Weight:154.25

Speicherung:

Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (272 KB)

SDS

COA

(-)-Menthone Chemical Structure

CAS. Nr.: 14073-97-3

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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

This product is a controlled substance, please contact local distributor for purchase. This product is a controlled substance and not for sale in your territory.

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Data Download

Data Sheet (272 KB)

SDS

COA

Handling Instructions (2659 KB)

Other Forms of (-)-Menthone:

Menthone
Auf Lager

(-)-Menthone-d₈
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(-)-Menthone (Standard)
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To place orders, for customer services and technical support, please contact:

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Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec

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Biologische Aktivität

Beschreibung

Chemical Information

Lösungsmittel & Löslichkeit

In Vitro

In Vivo

Reinheit & Dokumentation

Verweise

Help & FAQs

Classifications

Bioz

Biologische Aktivität

Beschreibung

(-)-Menthone is a monoterpene component of the essential oil of maturing peppermint. (+)-Neomenthyl-β-d-glucoside is a metabolite of (-)-Menthone^[1].Mortality of two biological forms of Anopheles stephensi(larvae) exposed to about 45 ppm (-)-Menthone is 27.67% and 94.92%. ^[2]

Chemical Information

CAS. Nr. 14073-97-3

Appearance Liquid (Density: 0.893 g/cm³)

Molecular Weight 154.25

Formel C₁₀H₁₈O

Color Colorless to light yellow

SMILES

O=C1[C@H](C(C)C)CC[C@@H](C)C1

Synonyms

L-Menthone

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Plants

other families

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Pure form -20°C 3 years

In solvent -80°C 6 months

-20°C 1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (648.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

6.4830 mL

32.4149 mL

64.8298 mL

5 mM

1.2966 mL

6.4830 mL

12.9660 mL

10 mM

0.6483 mL

3.2415 mL

6.4830 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=
Konzentration Konzentration

×
Volumen Volumen

×
Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

×

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

=

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

×

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:

To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.

The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO    40% PEG300    5% Tween-80    45% Saline
Solubility: ≥ 2.5 mg/mL (16.21 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.

Protocol 2

Add each solvent one by one: 10% DMSO    90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (16.21 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

Protocol 3

Add each solvent one by one: 10% DMSO    90% Corn Oil
Solubility: ≥ 2.5 mg/mL (16.21 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg

Animal Weight (Per Animal) Animal Weight (Per Animal)
g

Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL

Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

%
+

+
%
Tween-80 + +

%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact
MedChemExpress (MCE) .

Tel: 609-228-6898
E-mail: [email protected]
Technical Support: [email protected]

Method for preparing in vivo working solution for animal experiments:
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Saline .

Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)

SDS (394 KB)

English - EN (394 KB)

Français - FR (394 KB)

Deutsch - DE (394 KB)

Norwegian - NO (394 KB)

Español - ES (394 KB)

Swedish - SV (394 KB)

Italian - IT (394 KB)

Korean - KR (394 KB)

Portuguese - PT (394 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

Verweise

[1]. R Croteau, et al. Metabolism of Monoterpenes: Demonstration of (+)-Neomenthyl-beta-d-Glucoside as a Major Metabolite of (-)-Menthone in Peppermint (Mentha Piperita). Plant Physiol. 1979 Aug;64(2):169-75. [Content Brief]

[2]. Dehghankar M, et al. Bioactivities of rose-scented geranium nanoemulsions against the larvae of Anopheles stephensi and their gut bacteria. PLoS One. 2021 Feb;16(2):e0246470.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg

DMSO 1 mM 6.4830 mL 32.4149 mL 64.8298 mL 162.0746 mL

5 mM 1.2966 mL 6.4830 mL 12.9660 mL 32.4149 mL

10 mM 0.6483 mL 3.2415 mL 6.4830 mL 16.2075 mL

15 mM 0.4322 mL 2.1610 mL 4.3220 mL 10.8050 mL

20 mM 0.3241 mL 1.6207 mL 3.2415 mL 8.1037 mL

25 mM 0.2593 mL 1.2966 mL 2.5932 mL 6.4830 mL

30 mM 0.2161 mL 1.0805 mL 2.1610 mL 5.4025 mL

40 mM 0.1621 mL 0.8104 mL 1.6207 mL 4.0519 mL

50 mM 0.1297 mL 0.6483 mL 1.2966 mL 3.2415 mL

60 mM 0.1080 mL 0.5402 mL 1.0805 mL 2.7012 mL

80 mM 0.0810 mL 0.4052 mL 0.8104 mL 2.0259 mL

100 mM 0.0648 mL 0.3241 mL 0.6483 mL 1.6207 mL

(-)-Menthone Related Classifications

HY-N7916 Related Classifications

Others

Environmental Pollutants

Disease Areas

Others

Natürliche Produkte

Disease Research Fields Plants Ketones, Aldehydes, Acids

Other Diseases other families

Lipids

Prenol Lipids

Others

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Keywords

(-)-Menthone
14073-97-3
L-Menthone
Environmental Pollutants
Inhibitor
inhibitor
inhibit

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