PEG1500
Based on 1 Customer Validation
PEG1500 can be used as an excipient, such as ointment base, lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.50%
- CAS. Nr.: 25322-68-3
- Molecular Weight:1500.00
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
The FDA has approved polyethylene glycol (PEG) for use as a vehicle or base in foods, cosmetics and pharmaceuticals, including injectable, topical, rectal and nasal formulations. PEG shows little toxicity, and is eliminated from the body intact by either the kidneys (for PEGs < 30 kDa) or in the faeces (for PEGs > 20 kDa). PEG lacks immunogenicity, and antibodies to PEG are generated in rabbits only if PEG is combined with highly immunogenic proteins[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 25322-68-3
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Appearance Oil
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Molecular Weight 1500.00
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Color Colorless to off-white
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SMILES
[H]OCCO[H].[n]
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Synonyms
Polyethylene glycol 1500
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (66.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 100 mg/mL (66.67 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Yang J, Shen MH. Polyethylene glycol-mediated cell fusion. Methods Mol Biol. 2006;325:59-66. [Content Brief]
[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99. [Content Brief]
[3]. Harris JM, et al. Effect of pegylation on pharmaceuticals. Nat Rev Drug Discov. 2003 Mar;2(3):214-21. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 0.6667 mL | 3.3333 mL | 6.6667 mL | 16.6667 mL |
| 5 mM | 0.1333 mL | 0.6667 mL | 1.3333 mL | 3.3333 mL | |
| 10 mM | 0.0667 mL | 0.3333 mL | 0.6667 mL | 1.6667 mL | |
| 15 mM | 0.0444 mL | 0.2222 mL | 0.4444 mL | 1.1111 mL | |
| 20 mM | 0.0333 mL | 0.1667 mL | 0.3333 mL | 0.8333 mL | |
| 25 mM | 0.0267 mL | 0.1333 mL | 0.2667 mL | 0.6667 mL | |
| 30 mM | 0.0222 mL | 0.1111 mL | 0.2222 mL | 0.5556 mL | |
| 40 mM | 0.0167 mL | 0.0833 mL | 0.1667 mL | 0.4167 mL | |
| 50 mM | 0.0133 mL | 0.0667 mL | 0.1333 mL | 0.3333 mL | |
| 60 mM | 0.0111 mL | 0.0556 mL | 0.1111 mL | 0.2778 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
PEG1500 Related Classifications
HY-Y0873E Related Classifications
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- PEG1500
- 25322-68-3
- Polyethylene glycol 1500
- PEG 1500
- PEG-1500
- Polyethylene glycol1500
- Polyethylene glycol-1500
- Environmental Pollutants
- Biochemical Assay Reagents
- pharmaceutical excipient
- pharmaceutical auxiliarie
- pharmaceutical ingredients
- inactive ingredients
- stability
- solubility
- processability
- absorption
- distribution
- metabolism
- and elimination (ADME)
- Inhibitor
- inhibitor
- inhibit