Phenaglycodol
Phenaglycodol belongs to the group of butanediolsa with anxiolytic and anticonvulsant porperties. Phenaglycodol has orally bioactivity.
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- CAS. Nr.: 79-93-6
- Formel: C11H15ClO2
- Molecular Weight:214.69
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Phenaglycodol (55-80 mg/kg, i.p., 1 time) has antiepileptic activity in mice[1].
Phenaglycodol (50-100 mg/kg, i.g., 1 time) has antiepileptic activity in monkey[1].
Phenaglycodol (130mg/kg, i.p., 1 time) lowers the concentration of Meprobamate in serum and brain[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Cat[1]
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Dosage:20 mg/kg
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Administration:Intraperitoneal Injection (i.p.)
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Result:Showed that cat became quiet.
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Animal Model:Monkey[1]
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Dosage:50-100 mg/kg
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Administration:Intragastric Gavage (i.g.)
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Result:Showed that monkey became less aggressive or less fearful.
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Animal Model:Mice[1]
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Dosage:55-80 mg/kg
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Administration:Intraperitoneal Injection (i.p.)
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Result:Showed a reduction in spontaneous activity and sit quietly.
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Animal Model:Female Rats(Sprague-Dawley, 170g)[2]
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Dosage:130 mg/kg
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Administration:Intraperitoneal Injection (i.p.)
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Result:Showed that the decrease of Meprobamate concentration in the serum and brain of the pretrealed rats was more rapid than that in control rats.
Chemical Information
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CAS. Nr. 79-93-6
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Molecular Weight 214.69
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Formel C11H15ClO2
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SMILES
ClC1=CC=C(C(C)(C(C)(C)O)O)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. G T JONES, et al. Mode of action of phenaglycodol, a new neurosedative agent. Proc Soc Exp Biol Med. 1956 Dec;93(3):528-31. [Content Brief]
[2]. R. KATO, et al. Induced Increase o f M eprobam ate M etabolism in R ats T reated w ith P hénobarbital or Phenaglycodol. Pharmacology (1970) 3 (2): 95–100. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Phenaglycodol Related Classifications
HY-105845 Related Classifications
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