PMQA
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn2+-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn2+ in living cells.
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- CAS. Nr.: 1263820-18-3
- Formel: C17H16N4O
- Molecular Weight:292.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Help & FAQs
Biologische Aktivität
After incubation with PMQA (20 μM) for 1 h, weak green fluorescence appeared, presumably caused by the probe capturing intracellular zinc from its native ligands since PMQA has high affinity for zinc[1].
The response of PMQA to Zn2+ can be reversed by N,N,N’,N’-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) or EDTA[1].
When the stock solution of PMQA (0.1 mM in Tris Buffer) is kept at room temperature for a week, there is no significant loss of PMQA determined by HPLC analysis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS. Nr. 1263820-18-3
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Molecular Weight 292.34
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Formel C17H16N4O
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SMILES
O=C(NC1=C2N=CC=CC2=CC=C1)CNCC3=NC=CC=C3
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Synonyms
Zn-green
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PMQA Related Classifications
HY-D1264 Related Classifications
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