PV1115
PV1115 is a potent and highly selective Chk2 inhibitor with an IC50 of 0.14 nM, 66000 nM, >100000 nM for Chk2, Chk1 and RSK2, respectively. PV1115 is situated within the ATP-binding pocket of Chk2.
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- CAS. Nr.: 1093793-10-2
- Formel: C20H19N7O3
- Molecular Weight:405.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
IC50: 0.14 nM (Chk2), 66000 nM (Chk1) and >100000 nM (RSK2)[1]
Chemical Information
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CAS. Nr. 1093793-10-2
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Molecular Weight 405.41
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Formel C20H19N7O3
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SMILES
O=C(NC1=CC=C(C=C1)/C(C)=N/NC2=NCCN2)C3=CC4=C(C([N+]([O-])=O)=CC=C4)N3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)